The breeds I would say wouldn't quite "fit" into our household:
Border Collies-waaaay to much energy/work level needed, I've heard my Dobe should be pretty energetic, but at 5 months he's just as content to sit on my feet all day and be petted
Beagles-my sister in laws Beagle used to follow me out in the fields when I was riding, and I could scream till I was blue in the face to have him "come" and he just kept his nose down and kept going....irritating to me!
St. Bernards-we have one now that drools up a storm. I knew what I was getting into too; had one when I lived at home....but I swear she didn't drool as much!
Cocker Spaniels-I'm sure it's not breed specific but e v e r y one I have met "piddled" on the floor when excited (submissive urination I know) you can pretty much guarantee when you go to my sil's house, Princess is going to meet you at the door, wiggling her tail and piddling at the same time.
At one time I would have said the "little yappy dogs" but I have started to grow fond of the cute little Pomeranians, Chi's, etc.