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has anyone ordered generic heartguard from here?:
http://www.petshed.com/products/category346.asp
am i safe ordering the generic?
second question, I have an aussie puppy and my breeder said she could have the MDR1 gene that causes problems when the dog gets ivermectin. but i've found something that says its ok to give the dogs with that gene mutation ivermectin because the dose isn't large enough:
"What heartworm prevention products can I use if my dog has the MDR1 mutation?
Fortunately, the dose of ivermectin, selamectin, milbemycin and moxidectin in the commercial heartworm preparations are low enough to be used safely even in dogs with the MDR1 mutation. It is only when the drugs are used at high doses, such as those used to treat mange (50 times higher dose than the heartworm prevention dose), that dogs with the mutation will develop neurological toxicity. Attempting to use large animal formulations of these drugs is likely to cause neurological toxicity because it is difficult to accurately measure "
source: http://www.vetmed.wsu.edu/depts-VCPL/FAQ.aspx
how does everyone feel about this? if you have a collie breed is it ok to give them this medicine?
http://www.petshed.com/products/category346.asp
am i safe ordering the generic?
second question, I have an aussie puppy and my breeder said she could have the MDR1 gene that causes problems when the dog gets ivermectin. but i've found something that says its ok to give the dogs with that gene mutation ivermectin because the dose isn't large enough:
"What heartworm prevention products can I use if my dog has the MDR1 mutation?
Fortunately, the dose of ivermectin, selamectin, milbemycin and moxidectin in the commercial heartworm preparations are low enough to be used safely even in dogs with the MDR1 mutation. It is only when the drugs are used at high doses, such as those used to treat mange (50 times higher dose than the heartworm prevention dose), that dogs with the mutation will develop neurological toxicity. Attempting to use large animal formulations of these drugs is likely to cause neurological toxicity because it is difficult to accurately measure "
source: http://www.vetmed.wsu.edu/depts-VCPL/FAQ.aspx
how does everyone feel about this? if you have a collie breed is it ok to give them this medicine?