Dear readers, some of you might already know our German project www.mdr1-defekt.de. On this homepage we show tested dogs and provide informations about this serious mutation within the MDR1 gene. Further we are looking for news about this defect in the mdr1 and today we were shocked about finding this information: http://www.avma.org/onlnews/javma/sep07/070915a.asp So as this text is quite difficult to understand (and I prefer to thinking it's not true what I understand ...) we have a question: Is it already usual to breed mutant/mutant collies to test avermectines and is our breed already used as experimental animals ? Or does this information say that these informations are plans for the future to find the right dosage? Can someone please explain this information for me in "easy words" ? Best regards from Germany, Kris As for our project - we already show more than 600 dogs from all over the world! And every owner worldwide is invited to send us pictures and results.