Some venomous reptiles are pretty low risk. Hognose snakes are venomous, but they're rear fanged and their venom is geared toward lizards and has little to no effect on humans. Plus their self defense mechanism involves defecating and playing dead, not biting, which further lowers risk of a bite.
I think every person who wants a hot animal should get a white lipped python. They should handle it every day for a full year. And EVERY time they get bit, they must put a sticky note on the front of the vivarium saying:
Today I was bit. If this was (species X) I would be in the hospital and have to receive 5-30 vials of antivenom at a cost of $12,000+ each, if the hospital even stocks the appropriate kind. If not, I am now dead.
At the end of a year, they should count up the sticky notes and really decide if the more toxic hot pets are for them.
Edit: I know a dude with over 100 rattlesnakes who also breeds unaltered gaboon vipers. He's EXTREMELY responsible. He also supplies harvested venom for making antivenom.