I know that almost any breed CAN be good with little dogs. But in general, I guess I should ask, what breeds would you NOT want to live with a little dog? I'm not gonna lie, I don't think I'd ever get a Pit Bull so long as I have a little dog, just from everything I've read about DA problems. I <33 German Shepherds but since my uncle got his girl, even though they DO get along, I think I've changed my mind on wanting a GSD and Jackson at the same time, lol. It would be too much work for just me, as the GSD is too mouthy still and bats her paws constantly and is very slowly learning how to be gentle with Jackson, but yeah, it would just be too much work by myself - I can only do it when my uncle is here with her. I don't know, in your experience, what larger breeds always tend to be pretty good with little dogs and aware of their size? I am in love with English mastiffs as of late and almost every one I've seen on youtube and in real life, is pretty gentle (even as pups for the most part) and often lays down to play with little ones. Most Goldens I've seen have always been great with little ones, but most Labs I've met have NOT simply because they have sooo much energy.