Study regarding seizures and behavior in Belgian Malin

Aleron

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This is a big read but really interesting:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680094/pdf/1471-2156-14-45.pdf

The frequency of the DAT-VNTR genotype was
significantly different across breeds in that study, where
the 1/1 genotype appeared to be over represented in the
Belgian Malinois breed (MAL) when compared with
other breeds [33]. This suggests but does not specifically
confirm differences in allele frequency of the
"1" allele in
MAL compared with other breeds [33]. We hypothesized
that over representation of this allele in MAL may be
associated with behaviors described in some MAL. Specif-
ically, some owners of MAL in America (AM-MAL) have
reported seizures and unpredictable behavioral changes
including owner reports of dogs "eyes glazing overâ€, dogs
lack of response to environmental stimuli, and loss of
behavioral inhibition that may include owner-directed
biting behavior (L. Lit, personal communication). Dogs
with severe behavioral changes may be euthanized as
they may represent a danger to humans and other dogs,
whereas dogs with such intermittent behavioral changes
may provide continuing challenges in training."
 

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