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Old 06-26-2013, 02:28 PM
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Aleron Aleron is offline
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Join Date: Feb 2011
Location: NE Ohio
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Default Study regarding seizures and behavior in Belgian Malin

This is a big read but really interesting:

http://www.ncbi.nlm.nih.gov/pmc/arti...2156-14-45.pdf

Quote:
The frequency of the DAT-VNTR genotype was
significantly different across breeds in that study, where
the 1/1 genotype appeared to be over represented in the
Belgian Malinois breed (MAL) when compared with
other breeds [33]. This suggests but does not specifically
confirm differences in allele frequency of the
"1" allele in
MAL compared with other breeds [33]. We hypothesized
that over representation of this allele in MAL may be
associated with behaviors described in some MAL. Specif-
ically, some owners of MAL in America (AM-MAL) have
reported seizures and unpredictable behavioral changes
including owner reports of dogs "eyes glazing over”, dogs
lack of response to environmental stimuli, and loss of
behavioral inhibition that may include owner-directed
biting behavior (L. Lit, personal communication). Dogs
with severe behavioral changes may be euthanized as
they may represent a danger to humans and other dogs,
whereas dogs with such intermittent behavioral changes
may provide continuing challenges in training."
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